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Ajinomoto Co.'s humectants grew out of research into the skin's natural moisturizing factors (NMFs). These products protect the skin from dryness, moisturize, promote elasticity and help keep skin healthy and fresh-looking. Ranging from amino acids to polymers, each product has its own particular characteristics. As a result, the most suitable product can be selected to meet the usage demands of a wide range of skincare and hair care products.

Structure of Skin humectants
NMF: Present in the horny layer, NMF plays an important role in
maintaining skin moisture.

Components of NMF humectants
Source: H.W.Spier, G.Pascher Der Hautarzt. Vol.7, 55-60 (1956)

PRODEW® 300-400

Prodew® is a highly effective moisturizer formulated with NMF (Natural Moisturizing Factor) components. It has excellent moisture absorption and retention capabilities. When sodium PCA and L-proline, the components of Prodew®, are mixed, they show a synergistic moisturizing effect.

  • PRODEW® 300
    Mixture of sodium PCA and L-proline has a synergistic moisturizing effect.
  • PRODEW® 400
    The composition is modeled after NMF and contains 8 kinds of amino acids.
Amino Acid Composition of Prodew® 400

Free Amino Acid Composition of Human Epidermis


PRODEW® 500 is the amino acid blend developed to achieve a new technology for hair care. Unlike the skin, the presence and the role of naturally occurring free amino acids in hair are not well known, but amino acids applied externally are known to interact with the hair to produce various cosmetic effects such as moisturizing, strengthening structure, color-protection, and the repair of surface damage. The amino acid component in PRODEW® 500 is modeled after the constituent amino acids of proteins existing in the CMC (Cell Membrane Complex).

Human Hair Structurehumectants


AQUADEW SPA-30 is an anionic polymeric humectant derived from aspartic acid. It is superior to other humectants in its hygroscopic properties as well as its moisturizing efficacy. AQUADEW SPA-30's affinity for skin is so strong it can actually be felt. AQUADEW SPA-30 leaves skin feeling moist, smooth to the touch, and completely unsticky. It also moisturizes hair and increases manageability, AQUADEW SPA-30 protects cuticles and helps prevent hair breakage and splitting.

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